Document Detail

Q fever endocarditis: a case report and review of the literature.
MedLine Citation:
PMID:  16835673     Owner:  NLM     Status:  MEDLINE    
The case of a 31-year-old man from Alberta diagnosed with Q fever endocarditis is presented. To the authors' knowledge, this is the first case of Q fever endocarditis diagnosed in the province of Alberta. The patient had undergone open valvulotomy for congenital aortic stenosis as an infant. He presented with congestive heart failure secondary to severe aortic regurgitation and underwent mechanical aortic valve replacement. Early failure of the mechanical prosthesis and numerous laboratory abnormalities prompted an investigation for endocarditis, which was initially negative. Markedly positive serology eventually established the diagnosis of chronic Q fever. The patient subsequently underwent a second aortic valve replacement following initiation of appropriate antimicrobials directed against Coxiella burnetii. The present report reviews the clinical presentation and diagnosis of Q fever endocarditis. It highlights the insidious and nonspecific nature of the presenting symptoms, and emphasizes the use of serology for diagnosis. Increased awareness and earlier diagnosis can significantly decrease the morbidity and mortality associated with this disease.
Marc W Deyell; Brian Chiu; David B Ross; Nanette Alvarez
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Canadian journal of cardiology     Volume:  22     ISSN:  0828-282X     ISO Abbreviation:  Can J Cardiol     Publication Date:  2006 Jul 
Date Detail:
Created Date:  2006-07-12     Completed Date:  2006-08-29     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  8510280     Medline TA:  Can J Cardiol     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  781-5     Citation Subset:  IM    
Division of General Internal Medicine, University of Calgary, Alberta, Canada.
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MeSH Terms
Antibodies, Bacterial / immunology
Coxiella burnetii / immunology,  isolation & purification
Diagnosis, Differential
Endocarditis, Bacterial / diagnosis,  etiology*,  microbiology
Follow-Up Studies
Magnetic Resonance Imaging
Q Fever / complications*,  diagnosis,  microbiology
Reg. No./Substance:
0/Antibodies, Bacterial

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