| Pyrrolnitrin analogues. XI--Synthesis and microbiological activity of new 1,4- and 1,5-diarylpyrroles. | |
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MedLine Citation:
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PMID: 4043377 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The synthesis and microbiological activities of new 1,4- and 1,5-diarylpyrroles is reported. Antimicrobial data in comparison with fungal antibiotic pyrrolnitrin confirm an interesting antimicotic activity of 1,4-diarylpyrroles. On the contrary 1,5-diarylpyrroles show antibacterial activity and an unexpected antimicotic activity. The position of the 4-nitrophenyl group at C4 or C5 of the pyrrole ring influences antibacterial activity. |
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Authors:
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G C Porretta; F Chimenti; M Biava; A Bolasco; M Scalzo; S Panico; N Simonetti; A Villa |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Il Farmaco; edizione scientifica Volume: 40 ISSN: 0430-0920 ISO Abbreviation: Farmaco Sci Publication Date: 1985 Aug |
Date Detail:
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Created Date: 1985-11-13 Completed Date: 1985-11-13 Revised Date: 2009-11-19 |
Medline Journal Info:
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Nlm Unique ID: 0370716 Medline TA: Farmaco Sci Country: ITALY |
Other Details:
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Languages: eng Pagination: 589-607 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anti-Bacterial Agents Anti-Infective Agents / chemical synthesis* Antifungal Agents / chemical synthesis* Chemical Phenomena Chemistry Fungi / drug effects Gram-Negative Bacteria / drug effects Gram-Positive Bacteria / drug effects Microbial Sensitivity Tests Pyrrolnitrin / analogs & derivatives, chemical synthesis*, pharmacology |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents; 0/Anti-Infective Agents; 0/Antifungal Agents; 1018-71-9/Pyrrolnitrin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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