| Pyroptosis: macrophage suicide exposes hidden invaders. | |
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MedLine Citation:
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PMID: 21256438 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Caspase-1 plays a key role in host defense through its dual function in inducing a pro-inflammatory cell death termed pyroptosis and in promoting the secretion of pro-inflammatory cytokines. A new study now highlights the specific importance of pyroptosis in resistance to intracellular pathogens. |
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Authors:
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Igor E Brodsky; Ruslan Medzhitov |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Current biology : CB Volume: 21 ISSN: 1879-0445 ISO Abbreviation: Curr. Biol. Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2011-01-24 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9107782 Medline TA: Curr Biol Country: England |
Other Details:
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Languages: eng Pagination: R72-5 Citation Subset: IM |
Copyright Information:
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Copyright © 2011 Elsevier Ltd. All rights reserved. |
Affiliation:
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Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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