Document Detail

Pyrophosphate arthropathy.
MedLine Citation:
PMID:  227047     Owner:  NLM     Status:  MEDLINE    
Pyrophosphate arthropathy has a wide spectrum of clinical symptoms and is a common cause of synovitis in the elderly. The acute "pseudogout" attack is the most commonly recognized, but chronic synovitis might be just as prevalent. Familial pyrophosphate arthropathy with a dominant autosomal heredity is a rare form, with an earlier debut and a more severe prognosis. Another rare expression of pyrophosphate arthropathy is severe joint destruction. The cause of pyrophosphate arthropathy is still unknown. Both individual reactivity and crystal properties determine the intensity of the inflammatory response to crystals.
A Bjelle
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Scandinavian journal of rheumatology     Volume:  8     ISSN:  0300-9742     ISO Abbreviation:  Scand. J. Rheumatol.     Publication Date:  1979  
Date Detail:
Created Date:  1979-12-20     Completed Date:  1979-12-20     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0321213     Medline TA:  Scand J Rheumatol     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  145-53     Citation Subset:  IM    
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MeSH Terms
Acute Disease
Anti-Inflammatory Agents / therapeutic use
Calcium Pyrophosphate / metabolism*
Cartilage, Articular / pathology
Chondrocalcinosis / genetics,  metabolism*,  pathology
Chronic Disease
Diphosphates / metabolism*
Intervertebral Disk / radiography
Knee Joint / radiography
Middle Aged
Synovial Fluid / cytology
Synovitis / pathology
Reg. No./Substance:
0/Anti-Inflammatory Agents; 0/Diphosphates; 10086-45-0/Calcium Pyrophosphate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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