| Pyridazines, LXXII: On the synthesis of azinium and diazinium compounds structurally related to pyridazomycin. | |
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MedLine Citation:
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PMID: 7611825 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Preparation of series of pyridine-, pyridazine-, and pyrazine-derived carboxamides bearing at the ring N-atom an alkyl side-chain with a terminal carboxylic group (7-11) or with a terminal acetylamino malonic ester moiety (13-17, 19-23) is described. Two desaza-pyridazomycin derivatives (24, 26) and homologs thereof (25, 27) were synthesised. The novel compounds which are structurally related to the antifungal antibiotic pyridazomycin were screened for antifungal activity: preliminary in vitro tests showed no activity. |
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Authors:
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J Easmon; G Heinisch; W Holzer; B Matuszczak |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Archiv der Pharmazie Volume: 328 ISSN: 0365-6233 ISO Abbreviation: Arch. Pharm. (Weinheim) Publication Date: 1995 Apr |
Date Detail:
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Created Date: 1995-08-17 Completed Date: 1995-08-17 Revised Date: 2009-11-19 |
Medline Journal Info:
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Nlm Unique ID: 0330167 Medline TA: Arch Pharm (Weinheim) Country: GERMANY |
Other Details:
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Languages: eng Pagination: 307-12 Citation Subset: IM |
Affiliation:
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Institute of Pharmaceutical Chemistry, University of Innsbruck, Austria. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antifungal Agents
/
chemical synthesis*,
pharmacology Fungi / drug effects Microbial Sensitivity Tests Pyrazines / chemical synthesis*, pharmacology Pyridazines / chemistry, pharmacology Pyridines / chemical synthesis*, pharmacology |
| Chemical | |
Reg. No./Substance:
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0/Antifungal Agents; 0/Pyrazines; 0/Pyridazines; 0/Pyridines; 115920-43-9/pyridazomycin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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