Document Detail


Pyrethroid exposure of the general population-is this due to diet.
MedLine Citation:
PMID:  12191872     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Inhabitants (1177) of a residential area in Frankfurt/Main have been investigated with respect to internal exposure to pyrethroids. Biological monitoring revealed a body burden of pyrethroids. The 95th per thousand for the urinary metabolites of pyrethroids, such as permethrin and cypermethrin, cis and trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane-1-carboxylic acid (cis-DCCA and trans-DCCA), was determined to be 0.5 and 1.4 microg/l, respectively. 95th per thousand for cis-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropane-1-carboxylic acid (DBCA), a specific metabolite of deltamethrin, and 4-fluoro-3-phenoxybenzoic acid (F-PBA), a metabolite of cyfluthrin, were 0.3 and 0.27 microg/l, respectively. The metabolic pattern found for these samples points out that pyrethroids are probably ingested orally with daily diet.
Authors:
Thomas Schettgen; Ursel Heudorf; Hans Drexler; Jürgen Angerer
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Toxicology letters     Volume:  134     ISSN:  0378-4274     ISO Abbreviation:  Toxicol. Lett.     Publication Date:  2002 Aug 
Date Detail:
Created Date:  2002-08-22     Completed Date:  2002-10-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7709027     Medline TA:  Toxicol Lett     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  141-5     Citation Subset:  IM    
Affiliation:
Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, Friedrich-Alexander-University of Erlangen-Nürnberg, Schillerstrasse 25/29, D-91054, Erlangen, Germany.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Biological Markers / analysis
Child
Child, Preschool
Diet*
Environmental Exposure / analysis*
Environmental Monitoring / methods*
Female
Germany
Humans
Infant
Insecticides / pharmacokinetics*,  urine
Male
Middle Aged
Pyrethrins / pharmacokinetics*,  urine
Chemical
Reg. No./Substance:
0/Biological Markers; 0/Insecticides; 0/Pyrethrins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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