| Pyogenic granulomas during isotretinoin therapy. | |
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MedLine Citation:
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PMID: 21886758 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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BACKGROUND: A review of scientific literature reveals a sparse documentation of periungual pyogenic granulomas as an adverse effect of isotretinoin therapy MAIN OBSERVATIONS: Periungual pyogenic granulomas appeared in four patients receiving isotretinoin therapy for severe acne. Oral and topical antibiotic treatments were ineffective and all cases spontaneously resolved once isotretinoin is discontinued. CONCLUSION: This report demonstrates the idiosyncratic nature of this side effect. We suggest that, although infection is possible due to the transformed nature of the normally protective skin barrier, oral and topical antibiotic treatments appear ineffective. Pyogenic granulomas spontaneously resolve once isotretinoin is discontinued. |
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Authors:
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Kathleen Armstrong; Miriam Weinstein |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of dermatological case reports Volume: 5 ISSN: 1898-7249 ISO Abbreviation: J Dermatol Case Rep Publication Date: 2011 Mar |
Date Detail:
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Created Date: 2011-09-02 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101493700 Medline TA: J Dermatol Case Rep Country: Poland |
Other Details:
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Languages: eng Pagination: 5-7 Citation Subset: - |
Affiliation:
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Paediatric Dermatology Hospital For Sick Children, University of Toronto, 555 University Avenue, Toronto, Ontario, Canada, M5G 1X8. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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