Document Detail


Pyogenic granulomas of the cornea.
MedLine Citation:
PMID:  9098262     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Pyogenic granulomas are vascular inflammatory lesions that represent an aberrant wound healing response. They typically arise from mucous membranes or skin. Pyogenic granulomas primarily involving the cornea have been rarely reported. METHODS: Between January 1983 and July 1994, 14 patients with histologically proven pyogenic granulomas of the cornea were treated. RESULTS: The precipitating event was a persistent epithelial defect in nine patients. Ocular surface disease was present in all patients. Predisposing conditions included indolent corneal ulceration, cry eye syndrome, trachoma, trichiasis, alkali burn, multiple topical drug use, previous orbital irradiation, and ocular cicatricial pemphigoid. CONCLUSIONS: Ophthalmologists should be aware that pyogenic granulomas may involve the cornea and include this entry in the differential diagnosis of tumors involving the limbus or cornea. The typical clinical appearance, rapid growth, minimal staining with rose bengal dye, response to topical steroids, and associated ocular surface disease help to distinguish this lesion from a neoplastic epithelial tumor of the conjunctiva or cornea.
Authors:
J A Cameron; M A Mahmood
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Ophthalmology     Volume:  102     ISSN:  0161-6420     ISO Abbreviation:  Ophthalmology     Publication Date:  1995 Nov 
Date Detail:
Created Date:  1997-05-09     Completed Date:  1997-05-09     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7802443     Medline TA:  Ophthalmology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1681-7     Citation Subset:  IM    
Affiliation:
King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Child
Combined Modality Therapy
Conjunctiva / pathology
Cornea / pathology*
Corneal Diseases / etiology,  pathology*,  therapy
Diagnosis, Differential
Diagnostic Errors
Female
Follow-Up Studies
Granuloma, Pyogenic / etiology,  pathology*,  therapy
Humans
Male
Middle Aged
Retrospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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