| Pyoderma gangrenosum with oral involvement - case report and review of the literature. | |
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MedLine Citation:
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PMID: 20737938 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Pyoderma gangrenosum (PG) is a rare, noninfectious neutrophilic dermatosis. Clinically, it begins with sterile pustules that rapidly progress into painful ulcers of variable depth and size with undermined violaceous borders. The diagnosis of PG is based on the history of an underlying disease, a typical clinical presentation, histopathology, and exclusion of other diseases. The peak incidence occurs between the ages of 20 to 50 years with women being more often affected than men. There have been very few reports of pyoderma gangrenosum with oral mucosal involvement. Oral lesions in previously reported cases have included ulcers of varying sizes from a few mm to several cm and have been reported to have been found on the tongue, soft and hard palate, buccal mucosa, and gingiva. Some of these oral lesions have been associated with ulcerative colitis, inflammatory bowel disease, and polycythemia rubra vera. A few cases were reported with biopsy findings, the histological picture being nonspecific, showing ulceration, and necrosis with inflammatory cell infiltrate. A peculiar case of pyoderma gangrenosum with an oral lesion is presented here, and the differential diagnosis is discussed. |
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Authors:
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Geetha Paramkusam; Venkateswarlu Meduri; Naresh Gangeshetty |
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Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: International journal of oral science Volume: 2 ISSN: 1674-2818 ISO Abbreviation: Int J Oral Sci Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-08-26 Completed Date: 2010-09-07 Revised Date: 2012-10-15 |
Medline Journal Info:
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Nlm Unique ID: 101504351 Medline TA: Int J Oral Sci Country: China |
Other Details:
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Languages: eng Pagination: 111-6 Citation Subset: D; IM |
Affiliation:
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Department of Oral Medicine and Radiology, Kaminein Institute of Dental Sciences, Nagonda, India. |
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anti-Infective Agents / therapeutic use Chlorhexidine / therapeutic use Dapsone / therapeutic use Drug Therapy, Combination Female Glucocorticoids / therapeutic use Humans Metronidazole / therapeutic use Oral Ulcer / drug therapy, etiology*, pathology Prednisolone / therapeutic use Pyoderma Gangrenosum / complications* Tooth Mobility / etiology* |
| Chemical | |
Reg. No./Substance:
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0/Anti-Infective Agents; 0/Glucocorticoids; 443-48-1/Metronidazole; 50-24-8/Prednisolone; 55-56-1/Chlorhexidine; 80-08-0/Dapsone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
| Full Text | |
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Journal Information Journal ID (nlm-ta): Int J Oral Sci Journal ID (iso-abbrev): Int J Oral Sci ISSN: 1674-2818 ISSN: 2049-3169 Publisher: Nature Publishing Group |
Article Information Download PDF  Copyright © 2010 West China School of Stomatology open-access: Received Day: 28 Month: 01 Year: 2010 Revision Received Day: 23 Month: 03 Year: 2010 Accepted Day: 23 Month: 03 Year: 2010 Print publication date: Month: 06 Year: 2010 pmc-release publication date: Day: 1 Month: 6 Year: 2010 Volume: 2 Issue: 2 First Page: 111 Last Page: 116 ID: 3470099 Publisher Item Identifier: ijos201016 DOI: 10.4248/IJOS10032 PubMed Id: 20737938 |
| Pyoderma Gangrenosum with Oral Involvement – Case Report and Review of the Literature | |
| Geetha Paramkusam1 | |
| Venkateswarlu Meduri1 | |
| Naresh Gangeshetty1* | |
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1Department of Oral Medicine and Radiology, Kaminein Institute of Dental Sciences, Nagonda, India |
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| *Department of Oral Medicine and Radiology, Kaminein Institute of Dental Sciences, Sreepuram, Narketpally, Nagonda, Andhra Pradesh, India E-mail: gnareshdr@gmail.com |
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Article Categories:
Keywords: pyoderma gangrenosum, oral lesion of pyoderma gangrenosum, diagnosis. |
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