Document Detail

Pyoderma gangrenosum in a patient with autoimmune haemolytic anaemia and complement deficiency.
MedLine Citation:
PMID:  10886151     Owner:  NLM     Status:  MEDLINE    
About 50% of cases of pyoderma gangrenosum (PG) are associated with a variety of systemic diseases. We describe a patient with severe PG on both legs who suffered from an autoimmune haemolytic anaemia in association with a congenital deficiency of complement factors C2 and C4. To the best of our knowledge, this constellation has not been previously reported.
E A Coors; P von den Driesch
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The British journal of dermatology     Volume:  143     ISSN:  0007-0963     ISO Abbreviation:  Br. J. Dermatol.     Publication Date:  2000 Jul 
Date Detail:
Created Date:  2000-08-31     Completed Date:  2000-08-31     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0004041     Medline TA:  Br J Dermatol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  154-6     Citation Subset:  IM    
Department of Dermatology, University of Erlangen-Nuremberg, Hartmannstr. 14, D-91052 Erlangen, Germany.
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MeSH Terms
Anemia, Hemolytic, Autoimmune / complications*,  drug therapy,  immunology
Anti-Inflammatory Agents / therapeutic use
Azathioprine / therapeutic use
Complement C2 / deficiency*
Complement C4 / deficiency*
Drug Therapy, Combination
Immunosuppressive Agents / therapeutic use
Methylprednisolone / therapeutic use
Prednisone / therapeutic use
Pyoderma Gangrenosum / drug therapy,  etiology*
Reg. No./Substance:
0/Anti-Inflammatory Agents; 0/Complement C2; 0/Complement C4; 0/Immunosuppressive Agents; 446-86-6/Azathioprine; 53-03-2/Prednisone; 83-43-2/Methylprednisolone

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