Document Detail

Pyeloureteral dynamics. Pelvic pressure and kidney function in partial long-term ureteric obstruction.
MedLine Citation:
PMID:  2922577     Owner:  NLM     Status:  MEDLINE    
In 10 pigs with reno-scintigraphically proven normal upper urinary tracts, a standardized partial obstruction of the left ureter was created at the lower kidney pole level. Three weeks later kidney function was scintigraphically reassessed and the pressure flow relationship in the flow range 0-20 ml/min outlined. The partially obstructed pelvic baseline pressure varied from 9.0 to 32.0 cmH2O. During perfusion small increases in pelvic pressure were seen at all flow rates in the individual cases and there was a linear relationship between pressure and flow. Compared to previous results of a similar but acute obstruction the results were identical in pressure ranges and pressure flow profile. This demonstrates, that a longitudinal stability in transport mechanism qualities is present also during the course of obstruction. The pelvic pressure at low flow rates was significantly correlated to kidney function depression, whereas perfusion pressures at high flow rates did not show any correlation, except at 20 ml/min. This clearly indicates, that the pelvic pressure at normal urine flow rate is an important factor in the pathogenesis of obstructive nephropathy.
J Mortensen; P Christiansen; N Harving; F Taagehøj-Jensen; J C Djurhuus
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Scandinavian journal of urology and nephrology     Volume:  23     ISSN:  0036-5599     ISO Abbreviation:  Scand. J. Urol. Nephrol.     Publication Date:  1989  
Date Detail:
Created Date:  1989-04-20     Completed Date:  1989-04-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0114501     Medline TA:  Scand J Urol Nephrol     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  25-9     Citation Subset:  IM    
Institute of Experimental Clinical Research, University of Aarhus, Denmark.
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MeSH Terms
Iodine Radioisotopes / diagnostic use
Iodohippuric Acid / diagnostic use
Kidney / physiopathology*,  radionuclide imaging
Kidney Pelvis / physiopathology
Radioisotope Renography
Time Factors
Ureteral Obstruction / physiopathology*
Reg. No./Substance:
0/Iodine Radioisotopes; 147-58-0/Iodohippuric Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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