Document Detail


Pyelonephritis in pregnancy: an update on treatment options for optimal outcomes.
MedLine Citation:
PMID:  20731473     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Acute pyelonephritis is one of the most common indications for antepartum hospitalization. When acute pyelonephritis is diagnosed, conventional treatment includes intravenous fluid and parenteral antibacterial administration. There are limited data by which to assess the superiority of one antibacterial regimen over the other in terms of efficacy, patient acceptance and safety for the developing fetus; however, it is important to consider antimicrobial resistance patterns in the local community when choosing an agent. Moreover, there are growing public health concerns regarding antimicrobial resistance to commonly prescribed medications for urinary tract infections in pregnancy. There is a small body of evidence to support the ambulatory treatment of pregnant women with pyelonephritis in the first and early second trimesters, but the majority of women will be managed as inpatients. This article provides a suggested algorithm for the treatment of pyelonephritis during pregnancy.
Authors:
Jennifer A Jolley; Deborah A Wing
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Drugs     Volume:  70     ISSN:  0012-6667     ISO Abbreviation:  Drugs     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-08-24     Completed Date:  2010-12-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7600076     Medline TA:  Drugs     Country:  New Zealand    
Other Details:
Languages:  eng     Pagination:  1643-55     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, University of California, Irvine, Orange, California 92868, USA.
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Algorithms
Animals
Anti-Bacterial Agents / adverse effects,  therapeutic use*
Drug Resistance, Bacterial
Female
Humans
Pregnancy
Pregnancy Complications / drug therapy*,  physiopathology
Pregnancy Trimester, First
Pregnancy Trimester, Second
Pyelonephritis / complications,  drug therapy*,  physiopathology
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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