Document Detail


Putaminal magnetic resonance imaging features at various magnetic field strengths in multiple system atrophy.
MedLine Citation:
PMID:  20623769     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We delineated the effects of magnetic field strength on signal intensities to facilitate the specific findings of multiple system atrophy (MSA). Fifteen patients with probable MSA were imaged by 0.35T fast spin-echo (FSE), 1.5T FSE, and 3.0T FSE using a consistent protocol, testing all field strengths on the same day. Sixty patients with probable Parkinson's disease (PD) also underwent imaging. Moderate or marked hyperintensity at the dorsolateral outer putaminal margin, hyperintensity of the putaminal body, hypointensity relative to the globus pallidus at the dorsolateral putaminal margin, and infratentorial signal changes were evaluated as specific findings for MSA. As the field strength increased, the occurrence of hyperintensity both at the dorsolateral outer putaminal margin and of the putaminal body decreased, while the occurrence of hypointensity at the dorsolateral putaminal margin increased in MSA. The occurrence of uniform mild hyperintensity of the outer putaminal margin was evident in 7% at 0.35T, 40% at 1.5T, and 47% at 3.0T in MSA and in 5% at 0.35T, 60% at 1.5T, and 75% at 3.0T in PD. However, no PD patients showed hyperintensity at the dorsolateral outer putaminal margin and that of the putaminal body. Putaminal magnetic resonance imaging (MRI) findings in MSA were altered considerably by magnetic field strength. The severity and distribution of signal changes are important for assessing putaminal MRI findings in MSA.
Authors:
Hirohisa Watanabe; Mizuki Ito; Hiroshi Fukatsu; Jo Senda; Naoki Atsuta; Tomotsugu Kaga; Shigetaka Kato; Masahisa Katsuno; Fumiaki Tanaka; Masaaki Hirayama; Shinji Naganawa; Gen Sobue
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Movement disorders : official journal of the Movement Disorder Society     Volume:  25     ISSN:  1531-8257     ISO Abbreviation:  Mov. Disord.     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-09-14     Completed Date:  2010-12-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8610688     Medline TA:  Mov Disord     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1916-23     Citation Subset:  IM    
Copyright Information:
© 2010 Movement Disorders Society.
Affiliation:
Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
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MeSH Terms
Descriptor/Qualifier:
Aged
Brain Mapping
Female
Globus Pallidus / pathology
Humans
Image Processing, Computer-Assisted
Magnetic Resonance Imaging / methods*
Male
Middle Aged
Multiple System Atrophy / pathology*
Parkinson Disease / pathology
Putamen / pathology*
Statistics, Nonparametric

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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