| Puromycin: a questionable drug for studying the mechanism of thyroid calorigenesis in vivo. | |
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MedLine Citation:
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PMID: 4853979 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Puromycin fails to alter minimal oxygen consumption of rats treated with thyroxine, provided the rectal temperatures of these rats are maintained at 37.8 degrees to 38.1 degrees C. The previously reported puromycin-induced decline in basal metabolic rate of thyroxine-treated rats may have been due to the hypothermia produced by this drug. |
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Authors:
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G E Bilder; W D Denckla |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Science (New York, N.Y.) Volume: 185 ISSN: 0036-8075 ISO Abbreviation: Science Publication Date: 1974 Sep |
Date Detail:
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Created Date: 1974-11-06 Completed Date: 1974-11-06 Revised Date: 2011-12-27 |
Medline Journal Info:
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Nlm Unique ID: 0404511 Medline TA: Science Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1060-1 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Basal Metabolism / drug effects* Body Temperature / drug effects* Oxygen Consumption / drug effects Puromycin / pharmacology* Rats Thyroxine / pharmacology* |
| Chemical | |
Reg. No./Substance:
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53-79-2/Puromycin; 7488-70-2/Thyroxine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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