Document Detail

Purinergic signaling in neural development.
MedLine Citation:
PMID:  21320621     Owner:  NLM     Status:  Publisher    
Extracellular purine and pyrimidine compounds induce a multiplicity of cellular signal pathways that can induce multiple trophic functions. They interact with other low molecular weight messengers, growth factors, and extracellular matrix components. An increasing number of studies now provide evidence for a role of purinergic signaling in neural development, including progenitor cell proliferation, cell migration, neuronal and glial maturation and differentiation, and cell death and survival. This brief overview highlights recent developments supporting a contribution of purinergic signaling to embryonic and adult neurogenesis.
Herbert Zimmermann
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-2-11
Journal Detail:
Title:  Seminars in cell & developmental biology     Volume:  -     ISSN:  1096-3634     ISO Abbreviation:  -     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-2-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9607332     Medline TA:  Semin Cell Dev Biol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011. Published by Elsevier Ltd.
Institute of Cell Biology and Neuroscience, Biocenter, Goethe-University, Max von Laue-Str. 9, 60438 Frankfurt am Main, Germany.
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