Document Detail

Pure alexia caused by separate lesions of the splenium and optic radiation.
MedLine Citation:
PMID:  20798952     Owner:  NLM     Status:  In-Data-Review    
Pure alexia is severe difficulty in reading and understanding written language but with normal oral language and writing abilities. We report a patient with pure alexia caused by two different infarct lesions in the left lateral thalamus and the left splenium of the corpus callosum. A 56-year-old right-handed man was admitted to hospital with right homonymous hemianopia associated with pure alexia. He could write kana characters but not kanji. His cranial magnetic resonance imaging revealed two different infarct lesions in the left optic radiation and the left splenium of the corpus callosum. Magnetic resonance angiography showed mild stenosis at the origin of the right vertebral artery and stenosis of the left distal posterior cerebral artery. The mechanism of developing pure alexia can be simply explained by disconnection. We assumed that agraphia of kanji was caused by the effect of ischemia and edema following transient obstruction in branches from the distal posterior cerebral artery.
Shinichiro Maeshima; Aiko Osawa; Keisuke Sujino; Takuya Fukuoka; Ichiro Deguchi; Norio Tanahashi
Publication Detail:
Type:  Journal Article     Date:  2010-08-27
Journal Detail:
Title:  Journal of neurology     Volume:  258     ISSN:  1432-1459     ISO Abbreviation:  J. Neurol.     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-02-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0423161     Medline TA:  J Neurol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  223-6     Citation Subset:  IM    
Department of Rehabilitation Medicine, Saitama Medical University International Medical Center, 1397-1 Yamane, Hidaka, Saitama, 350-1298, Japan,
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