Document Detail


Pure Protein Scaffolds from Pickering High Internal Phase Emulsion Template.
MedLine Citation:
PMID:  23060090     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The formation of hierarchical porous protein scaffolds from oil-in-water (o/w) high internal phase emulsions (HIPEs) stabilized by bovine serum albumin (BSA) protein nanoparticles (Pickering HIPE) is reported. The route consists of three principal steps. First, a stable o/w HIPE stabilized by BSA protein nanoparticles is formulated. Next, crosslinking the dispersed protein nanoparticles gives rise to a gel in the continuous water phase to freeze the emulsion's microstructure. Finally, removal of the oil components and water directly leads to a three dimensional, bimodal meso-macroporous protein scaffold, which is suitable for a wide range of biomedical applications.
Authors:
Zifu Li; Manda Xiao; Jianfang Wang; To Ngai
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-10-12
Journal Detail:
Title:  Macromolecular rapid communications     Volume:  -     ISSN:  1521-3927     ISO Abbreviation:  Macromol Rapid Commun     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9888239     Medline TA:  Macromol Rapid Commun     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Affiliation:
Department of Chemistry, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong.
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