Document Detail


Pupillary dilation lag is intermittently present in patients with a stable oculosympathetic defect (Horner syndrome).
MedLine Citation:
PMID:  17386292     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To examine the repeatability of detecting pupillary dilation lag in patients with Horner syndrome. DESIGN: Retrospective interventional study. METHODS: Setting: Single referral institution. Patient population: Fifteen patients with unilateral Horner syndrome and 16 subjects with physiologic anisocoria. Intervention procedure: Each subject underwent four pupillometric recordings in darkness. The asymmetry of pupillodilation between the two eyes was calculated as the change in anisocoria between five seconds and 15 seconds in darkness. Pupillary dilation lag was considered present if the asymmetry measured > or =0.4 mm. Main outcome measure: Asymmetry of pupillodilation over four determinations. RESULTS: All subjects demonstrated fluctuations in the calculated asymmetry of pupillodilation. Eight patients (53%) with Horner syndrome demonstrated dilation lag on the first determination; 13 patients (87%) eventually demonstrated it during four determinations. CONCLUSIONS: Pupillary dilation lag is intermittently present in most patients with Horner syndrome. Repeated observations improve the detection rate of dilation lag, a confirmatory sign of an oculosympathetic deficit. Its absence does not rule out Horner syndrome.
Authors:
Sylvain V Crippa; François-Xavier Borruat; Aki Kawasaki
Publication Detail:
Type:  Journal Article     Date:  2006-12-08
Journal Detail:
Title:  American journal of ophthalmology     Volume:  143     ISSN:  0002-9394     ISO Abbreviation:  Am. J. Ophthalmol.     Publication Date:  2007 Apr 
Date Detail:
Created Date:  2007-03-27     Completed Date:  2007-04-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370500     Medline TA:  Am J Ophthalmol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  712-5     Citation Subset:  AIM; IM    
Affiliation:
Department of Neuro-ophthalmology, Hôpital Ophtalmique Jules Gonin, Lausanne, Switzerland.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Child
Diagnostic Techniques, Ophthalmological
Female
Horner Syndrome / complications*,  physiopathology
Humans
Male
Middle Aged
Pupil / physiology
Pupil Disorders / etiology*,  physiopathology
Retrospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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