| Pupil size with and without adrenaline with diclofenac use before cataract surgery. | |
| | |
MedLine Citation:
|
PMID: 19631127 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
PURPOSE: To determine whether adrenaline in the irrigating solution is necessary when diclofenac eyedrops are used before cataract surgery. SETTING: Pasqua Hospital, Regina, Saskatchewan, Canada. METHODS: In this prospective randomized masked study, all patients used diclofenac eyedrops 2 days preoperatively. The pupils were dilated with a wick soaked in a dilating solution containing diclofenac. Patients were divided into 2 groups. One group had 0.5 mL of 1:1000 adrenaline in 500.0 mL of fortified balanced salt solution (BSS Plus) (adrenaline group). The other group did not (no-adrenaline group). The horizontal diameter of the pupils was measured with calipers. RESULTS: The study included 207 patients. There were no surgical complications. In the adrenaline group, the mean pupil size was 8.19 mm +/- 0.86 (SD) before the first incision, 8.14 +/- 0.87 mm after phacoemulsification, and 8.14 +/- 0.85 mm after cortical removal. In the no-adrenaline group, the means were 8.19 +/- 0.87 mm, 7.94 +/- 0.99 mm, and 7.87 +/-1.03 mm, respectively. The mean pupil constriction was 0.05 +/- 0.21 mm in the adrenaline group and 0.33 +/- 0.43 mm in the no-adrenaline group. The difference was statistically significant (Mann-Whitney test). Further analysis of preoperative pupil size showed a significant difference for smaller pupils only. CONCLUSIONS: When diclofenac eyedrops were used before cataract surgery, the smaller preoperative pupils constricted significantly less when adrenaline was added to the irrigating solution. This was not true for larger pupils. Thus, adrenaline in the irrigating solution does not appear necessary in eyes with large preoperative pupils. |
| | |
Authors:
|
Lindsay Ong-Tone; Ali Bell |
Related Documents
:
|
11291357 - Acute postoperative swelling after hand surgery: an exploratory, double-blind, randomis... 10696747 - The role of preoperative subconjunctival mydricaine and topical diclofenac sodium 0.1% ... 7165237 - Use of a new oral analgesic, propiram fumarate, in treating postoperative ocular pain. 11185727 - Efficacy and tolerance of harpagophytum procumbens versus diacerhein in treatment of os... 10472467 - Long-term results of posterior semicircular canal occlusion for intractable benign paro... 8686527 - Application of transcranial doppler sonography in surgical aspects of hypertensive puta... |
Publication Detail:
|
Type: Journal Article; Randomized Controlled Trial |
Journal Detail:
|
Title: Journal of cataract and refractive surgery Volume: 35 ISSN: 1873-4502 ISO Abbreviation: J Cataract Refract Surg Publication Date: 2009 Aug |
Date Detail:
|
Created Date: 2009-07-27 Completed Date: 2009-10-12 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8604171 Medline TA: J Cataract Refract Surg Country: United States |
Other Details:
|
Languages: eng Pagination: 1396-400 Citation Subset: IM |
Affiliation:
|
University of Saskatchewan and Pasqua Hospital, Regina Qu'Appelle Health Region, Regina, Saskatchewan, Canada. longtone@accesscomm.ca |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Acetates
/
administration & dosage Aged Aged, 80 and over Anti-Inflammatory Agents, Non-Steroidal / administration & dosage* Diclofenac / administration & dosage* Double-Blind Method Drug Combinations Epinephrine / administration & dosage* Female Humans Iris / drug effects* Irrigation Lens Implantation, Intraocular Male Middle Aged Minerals / administration & dosage Mydriatics / administration & dosage* Ophthalmic Solutions / administration & dosage Phacoemulsification* Prospective Studies Pupil / physiology* Sodium Chloride / administration & dosage |
| Chemical | |
Reg. No./Substance:
|
0/Acetates; 0/Anti-Inflammatory Agents, Non-Steroidal; 0/BSS solution; 0/Drug Combinations; 0/Minerals; 0/Mydriatics; 0/Ophthalmic Solutions; 15307-86-5/Diclofenac; 51-43-4/Epinephrine; 7647-14-5/Sodium Chloride |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Effects of spherical aberration on visual acuity at different contrasts.
Next Document: Comparison of near visual acuity and reading metrics in presbyopia correction.