Document Detail

Pumpless arteriovenous carbon dioxide removal: A novel simplified strategy for severe asthma in children.
MedLine Citation:
PMID:  22346033     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Status asthmaticus unresponsive to pharmacotherapy is conventionally managed with mechanical ventilation, which has its inherent challenges due to barotrauma, dynamic hyperinflation and autopositive end-expiratory pressure (auto-PEEP). Extracorporeal membrane oxygenation has been used as a last resort in respiratory failure due to refractory asthma; however, it entails many complications. In contrast, arteriovenous carbon dioxide removal (AVCO(2)R) is a novel strategy that has been shown to be highly effective in adults with acute respiratory failure. Only one pediatric case series of pediatric asthma managed with AVCO(2)R have been published so far. We herein report a case of severe asthma in a 9-year-old boy who developed severe hypercapnia (Pco2 97 mmHg) and acidosis (pH 7.09) despite being on mechanical ventilation. Within 4 h of initiation of AVCO(2)R, PCo(2) drastically reduced to near-normal levels. He was discharged on day 9 of hospital stay without any complications.
Avinash Aravantagi; Kamakshya P Patra; Suman Shekar; L Keith Scott
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine     Volume:  15     ISSN:  1998-359X     ISO Abbreviation:  Indian J Crit Care Med     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2012-02-20     Completed Date:  2012-08-23     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  101208863     Medline TA:  Indian J Crit Care Med     Country:  India    
Other Details:
Languages:  eng     Pagination:  224-6     Citation Subset:  -    
Critical Care Division, Department of Pediatrics, Louisiana State University Health Sciences Center, Shreveport, LA, USA.
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