| Pulsed low-intensity ultrasound enhances healing rate in the osteoperforated tibia in a rabbit model. | |
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MedLine Citation:
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PMID: 20182253 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: The effect of pulsed low-intensity ultrasound (PLIUS) on healing rate in osteoperforated rabbit tibia during the healing period was investigated. METHODS: Using dental drills, 2-mm through holes were drilled at the midshaft of the right tibia in 36 mature New Zealand white rabbits. Animals were then randomly divided into normal, placebo control, and PLIUS treatment (20 minutes/day, five times/week) groups, and were euthanized at Weeks 2, 4, and 6 postoperatively (n=4 for each group and time point). Normalized radiographic density of the medial, central, and lateral sides of the holes was measured immediately after surgery and then every 2 weeks up to 6 weeks. Animals were euthanized after specified time points, both right and left tibias were removed, and using a standard three-point bending tester, maximum force to break and stiffness of the bones were measured. RESULTS: It was revealed that, in control and treatment groups, radiographic and mechanical measures increased as the time point increased. Outcome measures were found to be significantly greater in the PLIUS treatment group compared with that of the control group at 4- and 6-week time points. CONCLUSIONS: It is concluded that PLIUS can enhance healing rates in osteoperforations. |
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Authors:
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Ali Esteki; Behzad Yasrebi; Azadeh Shadmehr |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of orthopaedic trauma Volume: 24 ISSN: 1531-2291 ISO Abbreviation: J Orthop Trauma Publication Date: 2010 Mar |
Date Detail:
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Created Date: 2010-02-25 Completed Date: 2010-05-13 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8807705 Medline TA: J Orthop Trauma Country: United States |
Other Details:
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Languages: eng Pagination: 170-5 Citation Subset: IM |
Affiliation:
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Department of Biomedical Engineering & Physics, School of Medicine, Shahid Beheshti University (Medical Campus), Tehran, Iran. aesteki@sbmu.ac.ir |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Bony Callus / physiology*, radiography Disease Models, Animal Fracture Healing / physiology* Osteotomy Pliability Rabbits Radiation Dosage Stress, Mechanical Tibia / injuries, physiology*, radiography Ultrasonic Therapy* |
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