Document Detail

Pulsed CO2 laser ablation of tissue: effect of mechanical properties.
MedLine Citation:
PMID:  2606495     Owner:  NLM     Status:  MEDLINE    
The ablation rate of guinea pig skin and bovine aorta, myocardium, and liver by a CO2 laser emitting 2-microseconds-long pulses was quantified. Ablation efficiency was found to be strongly dependent upon the ultimate tensile strength of the tissue; the ablation efficiency of liver is seven times that of skin. Gluteraldehyde cross linking of skin, which is known to greatly increase tissue stiffness but not significantly affect ultimate tensile strength, did not change the ablation rate. The water content of the tissues, which largely determines the optical and thermal properties, was measured and found to vary only slightly. The results demonstrate that tissue mechanical properties are important in the interpretation and modeling of pulsed laser ablation of tissue and that variations in these mechanical properties can lead to drastically different cutting rates for different tissues.
J T Walsh; T F Deutsch
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Publication Detail:
Type:  In Vitro; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  IEEE transactions on bio-medical engineering     Volume:  36     ISSN:  0018-9294     ISO Abbreviation:  IEEE Trans Biomed Eng     Publication Date:  1989 Dec 
Date Detail:
Created Date:  1990-02-13     Completed Date:  1990-02-13     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0012737     Medline TA:  IEEE Trans Biomed Eng     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1195-201     Citation Subset:  IM    
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MeSH Terms
Aorta, Thoracic / analysis,  surgery
Body Water / analysis
Cardiac Surgical Procedures
Guinea Pigs
Laser Therapy*
Liver / analysis,  surgery
Myocardium / analysis
Skin / analysis,  surgery
Tensile Strength

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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