| Pulse oximetry, severe retinopathy, and outcome at one year in babies of less than 28 weeks gestation. | |
| | |
MedLine Citation:
|
PMID: 11207226 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
AIM: To determine whether differing policies with regard to the control of oxygen saturation have any impact on the number of babies who develop retinopathy of prematurity and the number surviving with or without signs of cerebral palsy at one year. METHODS: An examination of the case notes of all the 295 babies who survived infancy after delivery before 28 weeks gestation in the north of England in 1990-1994. RESULTS: Babies given enough supplemental oxygen to maintain an oxygen saturation of 88-98%, as measured by pulse oximetry, for at least the first 8 weeks of life developed retinopathy of prematurity severe enough to be treated with cryotherapy four times as often as babies only given enough oxygen to maintain an oxygen saturation of 70-90% (27.2% v 6.2%). Surviving babies were also ventilated longer (31.4 v 13.9 days), more likely to be in oxygen at a postmenstrual age of 36 weeks (46% v 18 %), and more likely to have a weight below the third centile at discharge (45% v 17%). There was no difference in the proportion who survived infancy (53% v 52%) or who later developed cerebral palsy (17% v 15%). The lowest incidence of retinopathy in the study was associated with a policy that made little use of arterial lines. CONCLUSIONS: Attempts to keep oxygen saturation at a normal "physiological" level may do more harm than good in babies of less than 28 weeks gestation. |
| | |
Authors:
|
W Tin; D W Milligan; P Pennefather; E Hey |
Related Documents
:
|
7519346 - Developmental outcome of infants treated with extracorporeal membrane oxygenation (ecmo... 2379386 - Inactivation of heparin during extracorporeal circulation in infants. 7422396 - Transcutaneous oxygen tension of newborn infants in different behavioral states. 10713406 - Spontaneous oscillation of oxy- and deoxy- hemoglobin changes with a phase difference t... 10392146 - Detection of hearing loss in infants. 15663126 - Trends in the cause of late fetal death, 1982-2000. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Archives of disease in childhood. Fetal and neonatal edition Volume: 84 ISSN: 1359-2998 ISO Abbreviation: Arch. Dis. Child. Fetal Neonatal Ed. Publication Date: 2001 Mar |
Date Detail:
|
Created Date: 2001-03-14 Completed Date: 2001-05-10 Revised Date: 2009-11-18 |
Medline Journal Info:
|
Nlm Unique ID: 9501297 Medline TA: Arch Dis Child Fetal Neonatal Ed Country: England |
Other Details:
|
Languages: eng Pagination: F106-10 Citation Subset: AIM; IM |
Affiliation:
|
Department of Paediatrics, South Cleveland Hospital, Middlesbrough TS4 3BW, UK. wtin@freenet.co.uk |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Clinical Protocols Confidence Intervals Disease-Free Survival Female Humans Infant Infant, Newborn Infant, Premature / physiology* Male Oximetry / methods* Oxygen Inhalation Therapy / adverse effects Retinopathy of Prematurity / etiology* Retrospective Studies |
| Comments/Corrections | |
Comment In:
|
Arch Dis Child Fetal Neonatal Ed. 2001 May;84(3):F149
[PMID:
11320038
]
Arch Dis Child Fetal Neonatal Ed. 2001 Jul;85(1):F75 [PMID: 11420331 ] Arch Dis Child Fetal Neonatal Ed. 2001 May;84(3):F149-50 [PMID: 11351984 ] Arch Dis Child Fetal Neonatal Ed. 2001 Jul;85(1):F75-6 [PMID: 11455942 ] |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Hepatic iron storage in very low birthweight infants after multiple blood transfusions.
Next Document: Cerebral palsy in the surviving twin associated with infant death of the co-twin.