| Pulse oximetry saturation to fraction inspired oxygen ratio as a measure of hypoxia under general anesthesia and the influence of positive end-expiratory pressure. | |
| | |
MedLine Citation:
|
PMID: 20655696 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
PURPOSE: In ICU patients with acute lung injury, the pulse oximetry saturation (Spo(2)) to fraction of inspired oxygen (Fio(2)) (S/F) ratio is a reliable surrogate measure for the P/F (Pao(2)/Fio(2)) ratio. Our goal was to determine the correlation of the S/F to the P/F in a large sample of patients undergoing general anesthesia and the influence of positive end-expiratory pressure (PEEP) on this measure. METHODS: We studied adult general anesthetics performed with arterial blood gas analysis. Intraoperative data were collected from an anesthesia information system. The S/F ratios corresponding to P/F ratios of 300 were determined. RESULTS: A total of 4439 values were collected. Linear correlation between S/F and P/F was identified (r = 0.46; P < .01) with a P/F of 300 corresponding to an S/F of 206. The correlation was stronger in patients with 5 to 9 cm PEEP (r = 0.52; P < .01), more than 9 cm H(2)O PEEP (r = 0.68; P < .01), and a P/F ratio of 300 or less (r = 0.61; P < .01). CONCLUSION: The S/F correlates with the P/F in our cohort of patients undergoing general anesthesia, especially those ventilated with PEEP more than 9 cm H(2)O and/or with P/F less than 300. It has use as a noninvasive measure to screen for increased pulmonary dysfunction and to trend oxygenation during a general anesthetic. |
| | |
Authors:
|
Ravi S Tripathi; James M Blum; Andrew L Rosenberg; Kevin K Tremper |
Related Documents
:
|
6393026 - Measurement of cardiopulmonary function by rebreathing methodology in piglets. 17006066 - Mechanical ventilation with lower tidal volumes and positive end-expiratory pressure pr... 18412646 - The relationship between arterial po2 and mixed venous po2 in response to changes in po... 17656676 - Ardsnet ventilatory protocol and alveolar hyperinflation: role of positive end-expirato... 4020696 - Characteristics of the vagally driven non-adrenergic, non-cholinergic inhibitory innerv... 1191486 - Intracranial pressure during recovery from nitrous oxide and halothane anaesthesia in n... |
Publication Detail:
|
Type: Journal Article Date: 2010-07-23 |
Journal Detail:
|
Title: Journal of critical care Volume: 25 ISSN: 1557-8615 ISO Abbreviation: J Crit Care Publication Date: 2010 Sep |
Date Detail:
|
Created Date: 2010-09-14 Completed Date: 2010-12-13 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8610642 Medline TA: J Crit Care Country: United States |
Other Details:
|
Languages: eng Pagination: 542.e9-13 Citation Subset: IM |
Copyright Information:
|
Copyright © 2010 Elsevier Inc. All rights reserved. |
Affiliation:
|
Department of Anesthesiology, University of Michigan Health System, Ann Arbor, MI 48109, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Adult Aged Aged, 80 and over Anesthesia, General Anoxia / diagnosis* Female Humans Male Middle Aged Monitoring, Intraoperative* Oximetry / methods* Oxygen / blood* Positive-Pressure Respiration Reproducibility of Results Young Adult |
| Chemical | |
Reg. No./Substance:
|
7782-44-7/Oxygen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: How can we diagnose and better understand inflammatory myopathies? The usefulness of auto-antibodies...
Next Document: Survival and quality of life after tracheostomy for acute respiratory failure in patients with amyot...