Document Detail


Pulsatile luteinizing hormone disruption in depression.
MedLine Citation:
PMID:  15177697     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Two independent groups recently published data comparing pulsatile luteinizing hormone (LH) release between depressed and control women. Despite similar populations and LH sampling frequency, they reached different conclusions: Meller et al. [Am. J. Psych. 154 (1997) 1454] found disruption of normal LH pulsatility in depressed women, whereas Young et al. [Arch. Gen. Psych. 57 (2000) 1157] did not. To resolve this discrepancy, the current study applies a single, well-established statistical method, spectral analysis, to the two data sets and concludes that both depressed populations display significantly altered LH pulsatile release.
Authors:
Patricia Grambsch; Elizabeth A Young; William H Meller
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Psychoneuroendocrinology     Volume:  29     ISSN:  0306-4530     ISO Abbreviation:  Psychoneuroendocrinology     Publication Date:  2004 Aug 
Date Detail:
Created Date:  2004-06-04     Completed Date:  2004-09-21     Revised Date:  2011-12-06    
Medline Journal Info:
Nlm Unique ID:  7612148     Medline TA:  Psychoneuroendocrinology     Country:  England    
Other Details:
Languages:  eng     Pagination:  825-9     Citation Subset:  IM    
Affiliation:
Division of Biostatistics, School of Public Health MMC303, University of Minnesota, 412 Delaware Street SE, Mayo A-460, Minneapolis, MN 55455, USA. pat@biostat.umn.edu
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MeSH Terms
Descriptor/Qualifier:
Adult
Data Interpretation, Statistical
Depressive Disorder / blood*
Female
Follicular Phase / blood*
Fourier Analysis
Humans
Hypothalamo-Hypophyseal System / physiopathology*
Luteal Phase / blood*
Luteinizing Hormone / blood*
Middle Aged
Models, Biological*
Periodicity
Grant Support
ID/Acronym/Agency:
MH-01931/MH/NIMH NIH HHS; MH-19815/MH/NIMH NIH HHS; MH-52287/MH/NIMH NIH HHS; MN-50030/MN/OMHHE CDC HHS; RR-00042/RR/NCRR NIH HHS; RR-00400/RR/NCRR NIH HHS
Chemical
Reg. No./Substance:
9002-67-9/Luteinizing Hormone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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