Document Detail

Pulpal necrosis with sickle cell anaemia.
MedLine Citation:
PMID:  15317563     Owner:  NLM     Status:  MEDLINE    
AIM: To investigate radiographic manifestations of sickle cell anaemia (SCA) and whether or not a pulpal necrosis may develop without a pathological history. METHODOLOGY: Thirty-six patients with homozygous SCA were evaluated, and a further 36 individuals without SCA were included in the study as a control group. All 72 patients participating in the study ranged between the ages of 16 and 40 years. General and dental histories of the individuals were recorded. Electrical pulp test, percussion and thermal tests were applied to all the teeth having no restorations. Orthopantomograms of all the subjects were taken. Data obtained from questionnaires, sensitivity tests and radiographic examinations were evaluated by chi-square and Fischer's exact test. RESULTS: Fifty-one (6%) of the teeth having no restorations or history of trauma were determined as being nonvital in the SCA group. In 30 (83%) of these patients orofacial and dental pain with no obvious cause was detected and in 24 (67%) of the patients the quality of the bone tissue as examined radiologically had deteriorated. In eight (22%) of the patients cortical thinning and irregularity in the mandible was noted. A statistically significant difference between the SCA and control groups (P < 0.05) was found in terms of pulpal sensitivity and radiological findings. CONCLUSION: SCA is a genetic and systemic disease which may cause pulp necrosis without necessarily having an identifiable aetiology. SCA causes radiographically observable differences in jaw structure especially in the mandible.
A Demirbaş Kaya; B O Aktener; C Unsal
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International endodontic journal     Volume:  37     ISSN:  0143-2885     ISO Abbreviation:  Int Endod J     Publication Date:  2004 Sep 
Date Detail:
Created Date:  2004-08-19     Completed Date:  2004-10-18     Revised Date:  2008-08-07    
Medline Journal Info:
Nlm Unique ID:  8004996     Medline TA:  Int Endod J     Country:  England    
Other Details:
Languages:  eng     Pagination:  602-6     Citation Subset:  D    
Department of Restorative Dentistry and Endodontics, School of Dentistry, Ege University, Izmir, Turkey.
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MeSH Terms
Anemia, Sickle Cell / complications*,  radiography
Case-Control Studies
Dental Pulp Necrosis / etiology*,  radiography
Mandible / radiography*
Mandibular Diseases / etiology*,  radiography
Radiography, Panoramic
Tooth, Nonvital / etiology
Toothache / etiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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