Document Detail

Pulmonary venous waterfall and perivenous pressure in the living dog.
MedLine Citation:
PMID:  1120756     Owner:  NLM     Status:  MEDLINE    
Evidence has been obtained that a waterfall effect occurs in the pulmonary veins of the living dog. Anesthetized open-chest dogs were used. Small catheters were passed from the left atrium retrogradely up the pulmonary veins and venous tributaries until they finally pierced the venous walls. They were then pulled out through the surface of the lung until their bellshaped inner ends wedged in small side branches of the vein. They were used to measure upstream venous pressures via the occluded tributary without occlusion of the vein. The pulmonary lymphatics and bronchial circulation were untouched. Alveolar pressure (transpulmonary pressure, Ptp) was held constant during the periods of measurement. We found that intrapulmonary (upstream) venous pressures did not rise with elevation of left atrial (downstream) pressures at any Ptp until a pressure of at least 7 cmH2O above the base of the lung was exceeded. This left atrial pressure (below which a venous waterfall or flow-limiting segment effect was present) increased with Ptp when Ptp exceeded about 15 cmH2O. The waterfall occurs in the larger veins at the lung surface. Its presence and location suggest that intrapulmonary veins in the living animal are held open by the surrounding lung tissue and that neither the flow through them nor their contained volume is influenced by left atrial pressure when this is low.
H C Smith; J Butler
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Journal of applied physiology     Volume:  38     ISSN:  0021-8987     ISO Abbreviation:  J Appl Physiol     Publication Date:  1975 Feb 
Date Detail:
Created Date:  1975-06-21     Completed Date:  1975-06-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0376576     Medline TA:  J Appl Physiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  304-8     Citation Subset:  IM    
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MeSH Terms
Atrial Function
Pulmonary Alveoli / blood supply
Pulmonary Circulation*
Pulmonary Veins / physiology*
Regional Blood Flow
Vascular Resistance
Venous Pressure*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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