Document Detail


Pulmonary veno-occlusive disease due to bleomycin therapy for lymphoma. Case reports.
MedLine Citation:
PMID:  6194564     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Two patients with lymphocytic lymphoma and bleomycin-induced pulmonary toxicity were shown at autopsy to have pulmonary venular alterations identical to pulmonary veno-occlusive disease (PVOD). While hepatic veno-occlusive disease due to alkylating agents has been reported, I am unaware of any report of PVOD related to bleomycin therapy.
Authors:
A G Rose
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde     Volume:  64     ISSN:  0256-9574     ISO Abbreviation:  S. Afr. Med. J.     Publication Date:  1983 Oct 
Date Detail:
Created Date:  1983-11-23     Completed Date:  1983-11-23     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0404520     Medline TA:  S Afr Med J     Country:  SOUTH AFRICA    
Other Details:
Languages:  eng     Pagination:  636-8     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Bleomycin / adverse effects*
Constriction, Pathologic / chemically induced
Humans
Lymphoma / drug therapy*
Male
Middle Aged
Pulmonary Veins / drug effects,  pathology*
Thrombosis / chemically induced*
Venules / pathology
Chemical
Reg. No./Substance:
11056-06-7/Bleomycin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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