| Pulmonary veno-occlusive disease after chemotherapy. | |
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MedLine Citation:
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PMID: 6187654 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A case of pulmonary veno-occlusive disease (PVOD) in a 41-year-old woman who had received chemotherapy (bleomycin, mitomycin-C, and cis-platinum) for metastatic cervical carcinoma is reported. Before her death, pulmonary hypertension and right ventricular heart failure had been attributed to lung toxicity induced by chemotherapy, but the postmortem findings were characteristic of PVOD. The authors support the view that PVOD is a syndrome, not a distinct entity, and present the case as a further example of the many situations in which PVOD can arise. Whether the lesions of the pulmonary veins developed as a result of the chemotherapy or whether the two conditions were associated by chance must remain, for now, a subject of speculation. Pathologists are urged to devote special attention to the examination of the pulmonary vessels in patients who have received chemotherapy. |
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Authors:
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R Joselson; M Warnock |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Human pathology Volume: 14 ISSN: 0046-8177 ISO Abbreviation: Hum. Pathol. Publication Date: 1983 Jan |
Date Detail:
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Created Date: 1983-05-05 Completed Date: 1983-05-05 Revised Date: 2005-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9421547 Medline TA: Hum Pathol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 88-91 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Bleomycin / adverse effects Carcinoma, Squamous Cell / drug therapy Cisplatin / adverse effects Cystitis / chemically induced Female Humans Lung / pathology Mitomycin Mitomycins / adverse effects Pulmonary Veins / pathology* Thrombosis / chemically induced*, pathology Uterine Cervical Neoplasms / drug therapy |
| Chemical | |
Reg. No./Substance:
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0/Mitomycins; 11056-06-7/Bleomycin; 15663-27-1/Cisplatin; 50-07-7/Mitomycin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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