| Pulmonary veno-occlusive disease after autologous bone marrow transplant in a child with stage IV neuroblastoma: case report and literature review. | |
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MedLine Citation:
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PMID: 12759629 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Pulmonary veno-occlusive disease (PVOD) is a rare, almost universally fatal complication of chemotherapy and bone marrow transplantation with few treatment options. A 19-month-old boy with stage 4 neuroblastoma with fatal PVOD following high-dose chemotherapy with autologous peripheral blood stem cell rescue is described here. A comprehensive literature review revealed 40 case reports of PVOD in oncology patients. Various therapeutic modalities were attempted, with four survivors. PVOD should be considered in patients with dyspnea and cardiomegaly. Less invasive diagnostic methods and more effective therapies are needed. |
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Authors:
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Angela D Trobaugh-Lotrario; Brian Greffe; Robin Deterding; Gail Deutsch; Ralph Quinones |
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Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: Journal of pediatric hematology/oncology Volume: 25 ISSN: 1077-4114 ISO Abbreviation: J. Pediatr. Hematol. Oncol. Publication Date: 2003 May |
Date Detail:
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Created Date: 2003-05-21 Completed Date: 2003-06-06 Revised Date: 2011-10-06 |
Medline Journal Info:
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Nlm Unique ID: 9505928 Medline TA: J Pediatr Hematol Oncol Country: United States |
Other Details:
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Languages: eng Pagination: 405-9 Citation Subset: IM |
Affiliation:
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Section of Pediatric Hematology/Oncology/Bone Marrow Transplantation, Children's Hospital of Denver, Colorado, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Bone Marrow Transplantation / adverse effects* Child Female Humans Infant Male Neoplasm Staging Neuroblastoma / complications*, etiology*, pathology Pulmonary Veno-Occlusive Disease / complications*, etiology*, pathology Transplantation, Autologous / adverse effects |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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