| Pulmonary vein gas analysis for assessing donor lung function. | |
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MedLine Citation:
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PMID: 12022557 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Radial artery oxygenation (PaO2) is the standard method for assessing potential lung donors. This study was proposed to assess the use of pulmonary vein gases (PvO2) in selection of donor lung for transplantation. METHODS: We studied 170 lungs from 85 consecutive donors. Lungs were classified into group A, PaO2 and PvO2 > 300 mm Hg; group B, PaO2 < 300 mm Hg, and PvO2 > 300 mm Hg; and group C, PvO2 < 300 mm Hg. RESULTS: Lungs retrieved from group A and group B were used for transplantation. Allograft function, assessed by the arterial and alveolar oxygen tension ratio, was similar at 12 hours and at 24 hours after operation (0.69, 0.73, vs 0.70, 0.71, for groups A and B, respectively (p = 0.8, 0.7, respectively). Similar radiologic appearance was seen in both groups (p = 0.2). Median duration of intubation was also similar (p = 0.6). The 30-day mortality rate was 12% versus 11.3% (p = 0.8), and 1-year survival rate was 80% versus 82% (p = 0.8) for recipient received lungs from group A and B donors, respectively. CONCLUSIONS: Selective pulmonary veins analysis gives an accurate assessment of individual gas exchange in comparison with arterial PaO2, identifying more potential donor lungs for transplantation. |
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Authors:
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Tarek M Aziz; Ahmed El-Gamel; Rasheed A G Saad; Marcello Migliore; Colin S Campbell; Nizar A Yonan |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Annals of thoracic surgery Volume: 73 ISSN: 0003-4975 ISO Abbreviation: Ann. Thorac. Surg. Publication Date: 2002 May |
Date Detail:
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Created Date: 2002-05-22 Completed Date: 2002-06-10 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 15030100R Medline TA: Ann Thorac Surg Country: United States |
Other Details:
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Languages: eng Pagination: 1599-604; discussion 1604-5 Citation Subset: AIM; IM |
Affiliation:
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Transplant Unit, Wythenshawe Hospital, Manchester, United Kingdom. tarekaziz55@hotmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Cause of Death Female Graft Survival / physiology Humans Lung Transplantation / physiology* Male Middle Aged Oxygen / blood* Postoperative Complications / mortality Prognosis Pulmonary Gas Exchange / physiology Pulmonary Veins Survival Rate Tissue Donors* |
| Chemical | |
Reg. No./Substance:
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7782-44-7/Oxygen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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