Document Detail


Pulmonary tumor embolism: a rare cause of acute right heart failure with elevated D-dimers.
MedLine Citation:
PMID:  19057276     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report the case of a 49-year-old woman with a prior history of breast cancer who presented with a subacute course of progressive dyspnoea, culminating in cardiovascular collapse from acute right heart failure. D-dimer serum level was elevated. While a computed tomography of the chest was negative for pulmonary embolism, the autopsy study revealed multiple carcinomatous emboli in distal pulmonary arteries, veins, and lymphatics. Pulmonary tumor embolism may be more frequent than previously thought, and could be mistaken for pulmonary thrombo-embolism.
Authors:
Robert Kridel; Samir Myit; Jean-Claude Pache; Jean-Michel Gaspoz
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer     Volume:  3     ISSN:  1556-1380     ISO Abbreviation:  J Thorac Oncol     Publication Date:  2008 Dec 
Date Detail:
Created Date:  2008-12-05     Completed Date:  2009-03-04     Revised Date:  2009-05-22    
Medline Journal Info:
Nlm Unique ID:  101274235     Medline TA:  J Thorac Oncol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1482-3     Citation Subset:  IM    
Affiliation:
Department of Internal Medicine, Division of Oncology, Geneva University Hospitals, Geneva, Switzerland. robert.kridel@hcuge.ch
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MeSH Terms
Descriptor/Qualifier:
Adenocarcinoma / blood,  secondary*
Autopsy
Breast Neoplasms / pathology
Diagnosis, Differential
Dyspnea / diagnosis,  etiology
Fatal Outcome
Female
Fibrin Fibrinogen Degradation Products / metabolism*
Heart Failure / blood,  etiology*
Humans
Lung Neoplasms / blood,  secondary*
Lymphangitis / diagnosis,  etiology
Neoplastic Cells, Circulating / pathology*
Pulmonary Embolism / blood,  complications*
Pulmonary Heart Disease / blood,  etiology*
Tomography, X-Ray Computed
Grant Support
ID/Acronym/Agency:
//Howard Hughes Medical Institute; //Wellcome Trust
Chemical
Reg. No./Substance:
0/Fibrin Fibrinogen Degradation Products; 0/fibrin fragment D
Comments/Corrections
Comment In:
J Thorac Oncol. 2009 Jun;4(6):777; author reply 777-8   [PMID:  19461409 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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