| Pulmonary thrombotic microangiopathic hemolytic anemia treated successfully with anticoagulant monotherapy. | |
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MedLine Citation:
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PMID: 20558947 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Thrombotic microangiopathic hemolytic anemia (TMHA) caused by antiphospholipid syndrome (APS) is generally associated with renal or neurological complications and plasma exchange is the first line of treatment. We present the case of a 72-year-old woman with APS who had chronic TMHA and pulmonary hypertension without other major complications. TMHA and pulmonary hypertension were refractory to plasma exchange but were treated successfully with anticoagulant monotherapy. Contrast-enhanced computed tomography and perfusion scintigraphy did not detect signs of pulmonary embolism. TMHA localized in pulmonary microvasculature which causes pulmonary hypertension is a very rare complication of APS. |
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Authors:
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Kazuyoshi Ishigaki; Yasunobu Takizawa; Junko Maruyama; Keigo Setoguchi |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2010-06-15 |
Journal Detail:
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Title: Internal medicine (Tokyo, Japan) Volume: 49 ISSN: 1349-7235 ISO Abbreviation: Intern. Med. Publication Date: 2010 |
Date Detail:
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Created Date: 2010-06-18 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9204241 Medline TA: Intern Med Country: Japan |
Other Details:
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Languages: eng Pagination: 1217-20 Citation Subset: IM |
Affiliation:
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Department of Allergy and Immunological Diseases, Tokyo Metropolitan Komagome Hospital, Tokyo, Japan. kazuyoshi@mbe.nifty.com |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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