| Pulmonary thrombosis in steroid-sensitive nephrotic syndrome. | |
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MedLine Citation:
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PMID: 15778847 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Thrombo-embolic episodes are an uncommon but known complication of nephrotic syndrome. However, pulmonary thrombosis/thromboembolism is rare, especially in children. We describe the cases of two girls, aged 12 years, who presented with severe oedema in relapse. They had intermittent tachypnoea, and CT pulmonary angiography (CTPA) provided a less invasive and more definitive way of confirming pulmonary thrombosis/thromboembolism. They received heparin with resolution of the tachypnoea. Anticoagulation was continued for 6 months after the episode in one patient. They have been in remission for more than 1 year, and a thrombophilia screen does not indicate a predisposing tendency to the formation of clots. Pulmonary thrombosis/thromboembolism could present with subtle symptoms and needs prompt diagnosis and treatment to prevent a fatal outcome. |
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Authors:
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Pankaj V Deshpande; Mark Griffiths |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2005-03-19 |
Journal Detail:
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Title: Pediatric nephrology (Berlin, Germany) Volume: 20 ISSN: 0931-041X ISO Abbreviation: Pediatr. Nephrol. Publication Date: 2005 May |
Date Detail:
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Created Date: 2005-04-19 Completed Date: 2005-07-06 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8708728 Medline TA: Pediatr Nephrol Country: Germany |
Other Details:
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Languages: eng Pagination: 665-9 Citation Subset: IM |
Affiliation:
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Department of Paediatric Nephrology, Southampton University Hospitals Trust, Tremona Road, Southampton, S016 6YD, UK. deshpp@suht.swest.nhs.uk |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Anticoagulants
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therapeutic use Child Female Heparin / therapeutic use Humans Nephrotic Syndrome / complications*, drug therapy Pulmonary Embolism / complications*, drug therapy Steroids / therapeutic use |
| Chemical | |
Reg. No./Substance:
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0/Anticoagulants; 0/Steroids; 9005-49-6/Heparin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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