| Pulmonary thromboendarterectomy in adolescents and young adults. | |
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MedLine Citation:
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PMID: 20503288 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: Chronic thromboembolic pulmonary hypertension (CTEPH) occurs in patients with recurrent or chronic pulmonary embolism, and is a rare but potentially devastating disease in adolescents and young adults. Pulmonary thromboendarterectomy (PTE) is an important curative therapy for patients with CTEPH. The importance of this treatment may be under-appreciated and under-utilized in adolescents and young adults. STUDY DESIGN: We performed a chart review of all patients <24 years of age who had PTE performed for CTEPH at our institution from 2003-2009 (seven patients, average age 20.2 +/- 2.5 years, range 17-23 years, average BMI 34 +/- 12 kg/m(2)). All patients had their operations performed by a single surgeon. RESULTS: There were no deaths. Three of the seven patients were incorrectly diagnosed prior to the diagnosis of CTEPH. Right ventricular systolic pressure decreased from 61.3 +/- 19 mmHg pre-operatively to 31.8 +/- 5 mmHg post-operatively (P = 0.008). All patients reported symptomatic relief, and no patient has had recurrence of CTEPH. CONCLUSION: Although rare in the young patient, recurrent pulmonary emboli can have devastating consequences. The potentially lethal implications of CTEPH may be under-appreciated in adolescents and young adults. When indicated, PTE is a definitive, curative procedure with low morbidity and mortality. |
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Authors:
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Jonathan N Johnson; David J Driscoll; Christopher G A McGregor |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Pediatric pulmonology Volume: 45 ISSN: 1099-0496 ISO Abbreviation: Pediatr. Pulmonol. Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-05-26 Completed Date: 2010-09-14 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8510590 Medline TA: Pediatr Pulmonol Country: United States |
Other Details:
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Languages: eng Pagination: 614-8 Citation Subset: IM |
Affiliation:
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Division of Pediatric Cardiology, Department of Pediatrics, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Endarterectomy* Female Humans Hypertension, Pulmonary / physiopathology, surgery* Lung / surgery Male Pulmonary Artery / physiopathology, surgery Pulmonary Embolism / physiopathology, surgery* Treatment Outcome Young Adult |
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