Document Detail


Pulmonary and systemic hemodynamic responses to fentanyl in infants.
MedLine Citation:
PMID:  3994009     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Pulmonary and systemic hemodynamic responses to fentanyl were studied in 12 infants after repair of congenital heart defects. During controlled ventilation, hemodynamic responses to 25 micrograms/kg of fentanyl were measured. No significant changes were found in heart rate, cardiac index, mean pulmonary artery pressure, or pulmonary vascular resistance index 5 min after the fentanyl had been given. There were small but statistically significant decreases in mean arterial pressure and systemic vascular resistance index after fentanyl. We conclude that under the conditions of this study, pulmonary and systemic hemodynamics in infants are minimally altered by 25 micrograms/kg of fentanyl.
Authors:
P R Hickey; D D Hansen; D L Wessel; P Lang; R A Jonas
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Anesthesia and analgesia     Volume:  64     ISSN:  0003-2999     ISO Abbreviation:  Anesth. Analg.     Publication Date:  1985 May 
Date Detail:
Created Date:  1985-06-10     Completed Date:  1985-06-10     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  1310650     Medline TA:  Anesth Analg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  483-6     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Blood Pressure / drug effects
Cardiac Output / drug effects
Fentanyl / pharmacology*
Heart Rate / drug effects
Hemodynamics / drug effects*
Humans
Infant
Pulmonary Circulation / drug effects*
Vascular Resistance / drug effects
Chemical
Reg. No./Substance:
437-38-7/Fentanyl

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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