Document Detail


The pulmonary system during exercise in hypoxia and the cold.
MedLine Citation:
PMID:  19854797     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The demands for pulmonary O(2) and CO(2) transport in the exercising human are substantial. Fortunately, the regulatory and architectural limits of the pulmonary system meet the requirements of heavy exercise in most individuals. However, in some highly trained athletes the high metabolic demand of intense exercise is in excess of the capacity of the pulmonary system. Environmental considerations, in addition to those imposed by the demands of exercise, provide further physiological challenges that must be met. Winter athletes often encounter high-altitude hypoxia and cold, either transiently during competition or repeatedly during training. In this brief review, we examine the pulmonary system during acute and chronic exercise in hypoxic and cold environmental conditions. Observations from studies conducted in humans are emphasized in order to ask questions about regulation, plasticity and the limits of human physiology. We also highlight new findings and controversial questions that would benefit from additional study.
Authors:
A William Sheel; Meaghan J MacNutt; Jordan S Querido
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review     Date:  2009-10-23
Journal Detail:
Title:  Experimental physiology     Volume:  95     ISSN:  1469-445X     ISO Abbreviation:  Exp. Physiol.     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-02-17     Completed Date:  2010-05-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9002940     Medline TA:  Exp Physiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  422-30     Citation Subset:  IM    
Affiliation:
University of British Columbia, 6108 Thunderbird Boulevard, Vancouver, BC, Canada. bill.sheel@ubc.ca
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MeSH Terms
Descriptor/Qualifier:
Adaptation, Physiological / physiology
Altitude
Anoxia / physiopathology*
Cold Temperature*
Humans
Lung / physiology*
Pulmonary Gas Exchange / physiology*
Sports / physiology*
Grant Support
ID/Acronym/Agency:
//Canadian Institutes of Health Research

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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