Document Detail


Pulmonary stretch receptor activity during Partial Liquid Ventilation in Cats with Healthy Lungs.
MedLine Citation:
PMID:  15084808     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
AIM: To study whether pulmonary stretch receptor (PSR) activity in mechanically ventilated young cats with healthy lungs during partial liquid ventilation (PLV) is different from that during gas ventilation (GV). METHODS: In 10 young cats (4.4 +/- 0.4 months, 2.3 +/- 0.3 kg; mean +/- SD), PSR instantaneous impulse frequency (PSR fimp) was recorded from single fibres in the vagal nerve during GV and PLV with perfluorocarbon (30 ml/kg) at increasing positive inspiratory pressures (PIP; 1.2, 1.8, 2.2 and 2.7 kPa), and at a positive end-expiratory pressure of 0.5 kPa. RESULTS: All PSRs studied during GV maintained their phasic character with increased impulse frequency during inspiration during PLV. Peak PSRfimp was lower at PIP 1.2 kPa (p < 0.05) and at PIP 2.7 kPa (p = 0.10) during PLV than during GV, giving a lower number of PSR impulses at these two settings during PLV (p < 0.05). CONCLUSION: The phasic character of PSR activity is similar during GV and PLV. PSR activity is not higher during PLV than during GV in cats with healthy lungs, indicating no extensive stretching of the lung during PLV.
Authors:
Esther Rieger-Fackeldey; Richard Sindelar; Anders Jonzon; Andreas Schulze; Gunnar Sedin
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2004-04-13
Journal Detail:
Title:  Biology of the neonate     Volume:  86     ISSN:  0006-3126     ISO Abbreviation:  Biol. Neonate     Publication Date:  2004  
Date Detail:
Created Date:  2004-08-12     Completed Date:  2005-01-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0247551     Medline TA:  Biol Neonate     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  73-80     Citation Subset:  IM    
Copyright Information:
Copyright 2004 S. Karger AG, Basel
Affiliation:
Department of Women's and Children's Health and Department of Physiology, Uppsala University, Uppsala, Sweden. ester.fackeldey@kbh.uu.se
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MeSH Terms
Descriptor/Qualifier:
Animals
Arteries
Biomechanics
Cats
Liquid Ventilation*
Lung / physiology*
Oxygen / blood
Pulmonary Stretch Receptors / physiology*
Respiration, Artificial
Chemical
Reg. No./Substance:
7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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