Document Detail

Pulmonary sequestration in a child with acute myeloid leukemia.
MedLine Citation:
PMID:  7947016     Owner:  NLM     Status:  MEDLINE    
The article describes a relatively rare congenital anomaly that was difficult to diagnose in a 10-year-old child with acute nonlymphoblastic leukemia. Just at diagnosis of leukemia, the patient showed a pathologic chest radiograph because of a parenchymal thickening at the right lung apex. The presence of bronchopneumonia was suspected, and broad-spectrum antibiotic therapy was started with subsequent antifungal treatment for persistent fever and concurrent chemotherapy-induced marrow aplasia, which did not favor pulmonary infiltrate recovery. Continuous culture tests, including bronchial swab, proved negative for Koch-Weeks bacillus, fungal organisms, and other pathogens. Computed tomography, however, was suggestive of Aspergillus lung involvement, and apical segmentectomy was performed. The anatomic pathologist suggested the diagnosis of intralobar sequestration. In summary, when pulmonary pathology with an excavation is found in a leukemic child, one must consider the possibility of pulmonary sequestration complicated by an infectious disease.
S Strada; A Barzaghi; A Piroddi; G Bovo; A Brenna; C Ballabio; G Masera; C Uderzo
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatric hematology and oncology     Volume:  11     ISSN:  0888-0018     ISO Abbreviation:  Pediatr Hematol Oncol     Publication Date:    1994 Jul-Aug
Date Detail:
Created Date:  1994-12-08     Completed Date:  1994-12-08     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8700164     Medline TA:  Pediatr Hematol Oncol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  427-32     Citation Subset:  IM    
Clinica Pediatrica, Università di Milano, Italy.
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MeSH Terms
Bronchopulmonary Sequestration / complications,  diagnosis,  pathology*
Leukemia, Myeloid, Acute / pathology*

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