Document Detail

Pulmonary sarcoidosis in a patient with ankylosing spondylitis treated with infliximab.
MedLine Citation:
PMID:  17417999     Owner:  NLM     Status:  MEDLINE    
We present a case of a 34 year-old male diagnosed with ankylosing spondylitis. After two years of treatment with infliximab, the patient developed a clinical picture compatible with stage II thoracic sarcoidosis. These findings resulted in the interruption of infliximab therapy. The patient was not administered new treatment since respiratory function testing did not confirm harmful repercussions. After a follow-up of 1 year, the patient is asymptomatic and radiologic tests show complete resolution of pulmonary infiltrates and mediastinal and bilateral hilar lymphad- enopathy.
R Almodóvar; M Izquierdo; P Zarco; F Javier Quirós; R Mazzucchelli; B Steen
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Clinical and experimental rheumatology     Volume:  25     ISSN:  0392-856X     ISO Abbreviation:  Clin. Exp. Rheumatol.     Publication Date:    2007 Jan-Feb
Date Detail:
Created Date:  2007-04-09     Completed Date:  2007-04-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8308521     Medline TA:  Clin Exp Rheumatol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  99-101     Citation Subset:  IM    
Rheumatology Unit, Alcorcón Hospital Foundation, Madrid, Spain.
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MeSH Terms
Antibodies, Monoclonal / adverse effects*
Antirheumatic Agents / adverse effects*
Granuloma / pathology
Sarcoidosis, Pulmonary / chemically induced*,  pathology,  therapy
Spondylitis, Ankylosing / drug therapy
Tomography, Spiral Computed
Reg. No./Substance:
0/Antibodies, Monoclonal; 0/Antirheumatic Agents; 0/infliximab

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