| Pulmonary sarcoidosis: correlation of CT and histopathologic findings. | |
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MedLine Citation:
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PMID: 8372178 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: Computed tomographic (CT) findings of pulmonary sarcoidosis were correlated with histopathologic features determined at open lung biopsy or autopsy. MATERIALS AND METHODS: Eight patients (six men and two women, aged 22-65 years) with pulmonary sarcoidosis diagnosed at histologic examination were studied at CT with a high-spatial-frequency algorithm. RESULTS: The most frequent CT features were irregularly thickened bronchovascular bundles (seven of eight cases [88%]) and small nodules along vessels (four cases [50%]). These features corresponded to granulomas formed in the connective tissue sheath around the pulmonary vessels and airways. This characteristic CT appearance was the result of the bronchovascular distribution of sarcoid granulomas. Granulomas adjacent to the visceral pleura or formed in the pleura in four patients were correlated with pleural or subpleural involvement. Ground-glass attenuation, present in six patients (75%), did not correlate with alveolitis in any patient. CONCLUSION: CT is a valuable technique with which to visualize the characteristic location of sarcoid granulomas in the pulmonary parenchyma. |
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Authors:
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K Nishimura; H Itoh; M Kitaichi; S Nagai; T Izumi |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Radiology Volume: 189 ISSN: 0033-8419 ISO Abbreviation: Radiology Publication Date: 1993 Oct |
Date Detail:
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Created Date: 1993-10-14 Completed Date: 1993-10-14 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0401260 Medline TA: Radiology Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 105-9 Citation Subset: AIM; IM |
Affiliation:
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Chest Disease Research Institute, Kyoto University, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Autopsy Biopsy Bronchi / pathology Bronchography Female Humans Lung / blood supply, pathology, radiography Lung Diseases / pathology*, radiography* Lymph Nodes / pathology Male Middle Aged Pulmonary Alveoli / pathology, radiography Sarcoidosis / pathology*, radiography* Tomography, X-Ray Computed* / methods |
| Comments/Corrections | |
Erratum In:
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Radiology 1994 Mar;190(3):907 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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