| Pulmonary sarcoidosis and antiphospholipid syndrome. | |
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MedLine Citation:
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PMID: 16771926 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Various autoimmune diseases have been reported to occur in patients with sarcoidosis. However, coexistence of sarcoidosis and antiphospholipid syndrome (APS) is extremely rare. We describe a 59-year-old female patient with pulmonary sarcoidosis who had preceding APS. Her previous medical history consisted of a miscarriage and ischemic colitis. She was diagnosed as APS during the onset of a brainstem infarction with positive reaction to beta2-glycoprotein I-dependent anticardiolipin antibody. Two years later, chest CT revealed enlargement of the hilar and mediastinal lymph nodes and small nodules in the lung fields. Transbronchial lung biopsy demonstrated non-caseating epithelioid cell granuloma leading to the diagnosis of definite pulmonary sarcoidosis. This is the first APS case where pulmonary involvement with sarcoidosis has been confirmed through lung biopsy. Our case report suggests that APS should be recognized as an accompanying disorder of sarcoidosis. |
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Authors:
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Fumiyuki Takahashi; Michie Toba; Kazuhisa Takahashi; Shigeru Tominaga; Koichi Sato; Yoshiteru Morio; Yuta Nakao; Ken Tajima; Kayo Miura; Toshimasa Uekusa; Yoshinosuke Fukuchi |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Respirology (Carlton, Vic.) Volume: 11 ISSN: 1323-7799 ISO Abbreviation: Respirology Publication Date: 2006 Jul |
Date Detail:
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Created Date: 2006-06-14 Completed Date: 2006-11-02 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9616368 Medline TA: Respirology Country: Australia |
Other Details:
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Languages: eng Pagination: 506-8 Citation Subset: IM |
Affiliation:
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Department of Respiratory Medicine, Juntendo University, School of Medicine, Hongo, Tokyo, Japan. fumiyuki@med.juntendo.ac.jp |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Ambulatory Care Facilities Antiphospholipid Syndrome / diagnosis* Biopsy Female Follow-Up Studies Glycoproteins / immunology Granuloma / pathology Humans Lung / pathology, radiography, surgery Lymph Nodes / radiography Middle Aged Sarcoidosis, Pulmonary / diagnosis*, pathology Time Factors Tomography, X-Ray Computed beta 2-Glycoprotein I |
| Chemical | |
Reg. No./Substance:
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0/Glycoproteins; 0/beta 2-Glycoprotein I |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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