Document Detail


Pulmonary rehabilitation at moderate altitude: a 1-year follow-up.
MedLine Citation:
PMID:  7808577     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: In order to evaluate a pulmonary rehabilitation program (PRP) at moderate altitude (1560 m) 62 patients with obstructive lung disease were asked to participate; 37 patients completed a 1-year follow-up at sea level, and 25 patients dropped out. The exercise training program lasted for 10 weeks and consisted of a cycling and running program of 20 min daily, 5 days a week. METHODS: Incremental exercise testing, spirometry and histamine provocation tests were performed at sea level before the PRP, on admission to the Dutch Asthma Centre, Davos, after 5 weeks of exercise training, at discharge from the Centre and 6 and 12 months after discharge at sea level. RESULTS: The PRP led to an increase in exercise capacity of the 37 patients who also completed the follow-up as reflected by an increase in Wmax (from 104 +/- 44 watt on admission to 150 +/- 8 at discharge, p < 0.001). HRmax (145 +/- 19/min to 151 +/- 21, p < 0.001), Wmax/HR (0.71 +/- 0.26 watt/beat/min to 0.99 +/- 0.29, p < 0.001), VO2max (1.4 +/- 0.4 l/min to 1.9 +/- 0.6, p < 0.001) and VEmax (49 +/- 18 l/min to 78 +/- 24, p < 0.001) measured at discharge from the Dutch Asthma Centre after the PRP were significantly higher than before the PRP at incremental exercise testing. The group of 25 patients who dropped out showed corresponding improvements in these parameters after the PRP in Davos. The 37 patients who completed the follow-up showed at incremental exercise testing 1 year after the PRP that only two of these parameters were still significantly elevated: VO2max 1.8 +/- 0.6 (p < 0.001) and VEmax 61 +/- 21 (p < 0.001). One year after the PRP arterial PCO2 values at maximum exercise were significantly lower (5.2 +/- 0.8 kPa, p < 0.05) than the baseline values (5.5 +/- 0.9 kPa). CONCLUSIONS: PRP at moderate altitude results in an increase of exercise tolerance in patients with asthma or COPD, but significant long-term effects are few.
Authors:
D Bijl; B Speelberg; H T Folgering
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Netherlands journal of medicine     Volume:  45     ISSN:  0300-2977     ISO Abbreviation:  Neth J Med     Publication Date:  1994 Oct 
Date Detail:
Created Date:  1995-02-02     Completed Date:  1995-02-02     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0356133     Medline TA:  Neth J Med     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  154-61     Citation Subset:  IM; S    
Affiliation:
Dutch Asthma Centre, Davos, Switzerland.
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MeSH Terms
Descriptor/Qualifier:
Adult
Altitude*
Asthma / physiopathology,  rehabilitation*
Bronchial Provocation Tests
Exercise*
Exercise Test
Exercise Tolerance
Female
Follow-Up Studies
Histamine / diagnostic use
Humans
Lung Diseases, Obstructive / physiopathology,  rehabilitation*
Male
Middle Aged
Respiratory Function Tests
Chemical
Reg. No./Substance:
51-45-6/Histamine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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