Document Detail


Pulmonary plasma cell granuloma (inflammatory pseudotumor) with invasion of thoracic vertebra.
MedLine Citation:
PMID:  2366768     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Plasma cell granulomas (inflammatory pseudotumors) frequently appear as localized benign tumors of the lung in patients under 30 years of age. We describe the case of a 54-year-old woman with a plasma cell granuloma originating in the left lower lobe of lung and extending into the posterior mediastinum with destruction of the T8 vertebral body and pedicle. Distinctive histologic features included granulomatous aggregation of mature plasma cells around small blood vessels and direct invasion of the posterior mediastinum with subsequent dense fibrosis and bony destruction. Immunohistochemical studies revealed polyclonal kappa- and lambda-light chains in the proliferation of plasma cells.
Authors:
H Y Hong; M J Castelli; J L Walloch
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Mount Sinai journal of medicine, New York     Volume:  57     ISSN:  0027-2507     ISO Abbreviation:  Mt. Sinai J. Med.     Publication Date:  1990 Mar 
Date Detail:
Created Date:  1990-08-13     Completed Date:  1990-08-13     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0241032     Medline TA:  Mt Sinai J Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  117-21     Citation Subset:  IM    
Affiliation:
Department of Pathology, Loyola University Medical Center, Maywood, IL 60153.
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MeSH Terms
Descriptor/Qualifier:
Female
Fractures, Spontaneous / pathology
Granuloma / pathology*
Granuloma, Plasma Cell / complications,  pathology*,  surgery
Humans
Lung Diseases / complications,  pathology*,  surgery
Middle Aged
Spinal Diseases / pathology*
Thoracic Vertebrae / injuries,  pathology*

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