Document Detail

Pulmonary oil deposition in patients subjected to lymphography: Detection by thoracic photoscan and sputum examination.
MedLine Citation:
PMID:  4286715     Owner:  NLM     Status:  MEDLINE    
During clinical trials of intralymphatic therapy with radioiodinated ethiodized oil (Lipiodol Ultra-Fluid; Ethiodol) [LUF-I(131)] for malignant disease involving lymph nodes, significant pulmonary deposition of radioactive material was demonstrated by thoracic scan in each of five cases treated. Radioactivity was detected in sputum obtained from two cases. Induced sputum specimens were subsequently obtained from patients undergoing lymphography. Fat demonstrated in sputum was confirmed as Lipiodol in one of six patients tested. Sputum examination and use of tracer doses of LUF-I(131) plus photoscanning are suggested as sensitive methods of assessing the incidence of oil deposition in the lungs of patients undergoing lymphography. Despite limitation of the volume of oil injected, monitoring of the infusion, and absence of radiographic evidence of contrast medium in the lungs, some degree of pulmonary oil deposition appears to be an inevitable result of lymphography. Further study of lung dosimetry is being undertaken by the authors before clinical usage of endolymphatic radioisotope therapy is expanded.
P Richardson; E H Crosby; H A Bean; D Dexter
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Canadian Medical Association journal     Volume:  94     ISSN:  0008-4409     ISO Abbreviation:  Can Med Assoc J     Publication Date:  1966 May 
Date Detail:
Created Date:  1966-07-28     Completed Date:  1966-07-28     Revised Date:  2010-06-22    
Medline Journal Info:
Nlm Unique ID:  0414110     Medline TA:  Can Med Assoc J     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  1086-91     Citation Subset:  AIM; IM    
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MeSH Terms
Ethiodized Oil
Iodized Oil*
Lung Neoplasms / radiotherapy*
Lymphography / adverse effects*
Middle Aged
Radionuclide Imaging*
Radiotherapy Dosage
Reg. No./Substance:
8001-40-9/Iodized Oil; 8008-53-5/Ethiodized Oil

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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