| Pulmonary non-Hodgkin's lymphoma developed during long-term methotrexate therapy for rheumatoid arthritis. | |
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MedLine Citation:
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PMID: 20401724 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Methotrexate is effective in treating rheumatoid arthritis (RA). Some reports have discussed the possible association between methotrexate and lymphoma. Here, we report a case of pulmonary non-Hodgkin's lymphoma (NHL) developed after 11 years' methotrexate therapy for RA. Biopsy of the pulmonary mass demonstrated a diffuse large B-cell lymphoma. After withdrawal of methotrexate without any other intervention for 4 weeks, a significant reduction in the size of the lymphoma was observed. The causative relationship between methotrexate and pulmonary lymphoma is suggested by the persistent remission after stopping methotrexate therapy. |
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Authors:
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Huiying Wang; Dandan Wu; Hua Xiang; Aifeng Chen; Jin Liu |
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Publication Detail:
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Type: Journal Article Date: 2010-04-18 |
Journal Detail:
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Title: Rheumatology international Volume: 32 ISSN: 1437-160X ISO Abbreviation: Rheumatol. Int. Publication Date: 2012 Nov |
Date Detail:
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Created Date: 2012-11-26 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8206885 Medline TA: Rheumatol Int Country: Germany |
Other Details:
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Languages: eng Pagination: 3639-42 Citation Subset: IM |
Affiliation:
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Department of Respiratory Medicine, The Second Affiliated Hospital of Zhejiang University Medical School, Respiratory Institute of Zhejiang University, 88 Jiefang Road, 310009, Hangzhou, Zhejiang Province, People's Republic of China, w_huiying@yahoo.com. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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