Document Detail

Pulmonary manifestations of endocrine and metabolic disorders.
MedLine Citation:
PMID:  2689069     Owner:  NLM     Status:  MEDLINE    
In summary, there are a number of important respiratory manifestations of endocrine diseases. Hypothyroidism may be associated with respiratory failure that can be caused by a reduction in central respiratory drive, upper airway obstruction, and associated restrictive pulmonary function from pleural effusions or an intrinsic decrease in lung volumes. Hyperthyroidism can present with dyspnea as a major clinical manifestation because of the increase in central respiratory drive associated with thyrotoxicosis. Cardiac dysfunction associated with hyperthyroidism may lead to pulmonary edema in some patients. Hypoparathyroidism may occur acutely, especially after thyroid surgery and be associated with hypocalcemia and acute tetany, laryngeal stridor, and muscle weakness. Ovarian tumors, both benign and malignant, may present with unilateral or bilateral effusions. Finally, patients with diabetes mellitus are at increased risk of developing a variety of pulmonary disorders. Acute and chronic pulmonary infections are the most common respiratory abnormalities in patients with diabetes, although cardiogenic and noncardiogenic pulmonary edema can also be a complication of their disease.
T Brüssel; M A Matthay; B Chernow
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Review    
Journal Detail:
Title:  Clinics in chest medicine     Volume:  10     ISSN:  0272-5231     ISO Abbreviation:  Clin. Chest Med.     Publication Date:  1989 Dec 
Date Detail:
Created Date:  1990-02-01     Completed Date:  1990-02-01     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  7907612     Medline TA:  Clin Chest Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  645-53     Citation Subset:  IM    
Harvard Medical School, Boston, Massachusetts.
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MeSH Terms
Diabetes Complications
Endocrine System Diseases / complications*
Lung Diseases / etiology*
Metabolic Diseases / complications*
Thyroid Diseases / complications
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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