Document Detail

Pulmonary lymphoma developed during long-term methotrexate therapy for psoriasis.
MedLine Citation:
PMID:  17875071     Owner:  NLM     Status:  MEDLINE    
Low dose weekly administration of methotrexate has been thought to be effective for both rheumatoid arthritis (RA) and psoriasis. However, there is a possibility that methotrexate therapy may be oncogenic. This report presents a case of pulmonary lymphoma developed during long-term methotrexate therapy for psoriasis. Physicians should be aware that Epstein-Barr virus-associated lymphoproliferative disorders that occur during treatment with methotrexate are not specific to patients with RA.
Manabu Suzuki; Satoshi Hirano; Hideyuki Ito; Daisuke Matsubara; Kazuo Kubota; Yuichiro Takeda; Haruhito Sugiyama; Nobuyuki Kobayashi; Koichiro Kudo
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Respirology (Carlton, Vic.)     Volume:  12     ISSN:  1323-7799     ISO Abbreviation:  Respirology     Publication Date:  2007 Sep 
Date Detail:
Created Date:  2007-09-18     Completed Date:  2007-12-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9616368     Medline TA:  Respirology     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  774-6     Citation Subset:  IM    
Department of Respiratory Medicine, International Medical Center of Japan Hospital, Tokyo, Japan.
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MeSH Terms
Immunosuppressive Agents / administration & dosage,  adverse effects*
Lung / pathology
Lung Neoplasms / chemically induced*,  radiography
Lymphoma / chemically induced*,  radiography
Methotrexate / administration & dosage,  adverse effects*
Psoriasis / drug therapy*
Tomography, X-Ray Computed
Reg. No./Substance:
0/Immunosuppressive Agents; 59-05-2/Methotrexate

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