| Pulmonary infiltrates in patients with haematologic malignancies: transbronchial lung biopsy increases the diagnostic yield with respect to neoplastic infiltrates and toxic pneumonitis. | |
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MedLine Citation:
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PMID: 15133629 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We retrospectively evaluated 107 fiberoptic bronchoscopies with and without transbronchial lung biopsy (TBLB) in 98 consecutive patients with haematologic malignancies and pulmonary infiltrates. Bronchoalveolar lavage (BAL) was performed in 45 and BAL plus TBLB in 62 procedures. There was no procedure-related severe haemorrhage, pneumothorax or death. Infectious aetiology was identified in 26 of 107 (24%), toxic pneumonitis in 17 of 107 (16%) and neoplastic infiltration in 9 of 107 (8.5%) episodes. Combined BAL and TBLB was significantly superior to BAL alone with respect to the diagnosis of neoplastic infiltrates (p=0.008) and toxic pneumonitis (p<0.001) and should therefore be included in the diagnostic work-up of this patient cohort. |
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Authors:
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A Mulabecirovic; P Gaulhofer; H W Auner; H Popper; R Krause; C Hesse; H Sill |
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Publication Detail:
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Type: Journal Article Date: 2004-05-05 |
Journal Detail:
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Title: Annals of hematology Volume: 83 ISSN: 0939-5555 ISO Abbreviation: Ann. Hematol. Publication Date: 2004 Jul |
Date Detail:
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Created Date: 2004-06-01 Completed Date: 2004-09-20 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 9107334 Medline TA: Ann Hematol Country: Germany |
Other Details:
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Languages: eng Pagination: 420-2 Citation Subset: IM |
Affiliation:
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Division of Rheumatology, Medical University, Auenbruggerplatz 15, 8036 Graz, Austria. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Antineoplastic Agents / adverse effects, diagnostic use Biopsy* / adverse effects, methods, statistics & numerical data Bronchoalveolar Lavage Fluid Bronchoscopy Cohort Studies Disease Progression Female Fiber Optic Technology Hematologic Neoplasms / complications, diagnosis, pathology* Hemorrhage / etiology, prevention & control Humans Leukemic Infiltration Lung / pathology* Lung Diseases / diagnosis, etiology, pathology Male Middle Aged Myelodysplastic Syndromes / complications, diagnosis, pathology Platelet Transfusion Pneumonia / chemically induced, diagnosis, etiology, pathology Predictive Value of Tests Retrospective Studies |
| Chemical | |
Reg. No./Substance:
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0/Antineoplastic Agents |
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