Document Detail

Pulmonary impairment from chronic exposure to sulfur dioxide in a smelter.
MedLine Citation:
PMID:  879598     Owner:  NLM     Status:  MEDLINE    
The pulmonary function of 113 copper smelter workers was measured in 1973 and again in 1974 to asses the effects of chronic exposure to sulfur dioxide. Respiratory symptoms, smoking history, occupational history, and pulmonary function as measured by forced vital capacity and 1-sec forced expiratory volume were recorded. Exposures to sulfur dioxide, respirable particulates, sulfates, and copper were sampled at intervals throughout the year by personal monitoring. Exposure to 1.0 to 2.5 ppm of sulfur dioxide was associated with excessive loss of 1-sec forced expiratory volume during the year and an increase in respiratory symptoms, after controlling for smoking. No significant interaction between sulfur dioxide and concurrent exposure to respirable particulates on pulmonary function was found. Workers with 1-sec forced expiratory volume below normal on initial measurements (based on their age and height) showed evidence of even greater losses of pulmonary function related to sulfur dioxide exposure.
T J Smith; J M Peters; J C Reading; C H Castle
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  The American review of respiratory disease     Volume:  116     ISSN:  0003-0805     ISO Abbreviation:  Am. Rev. Respir. Dis.     Publication Date:  1977 Jul 
Date Detail:
Created Date:  1977-08-25     Completed Date:  1977-08-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370523     Medline TA:  Am Rev Respir Dis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  31-9     Citation Subset:  AIM; IM    
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MeSH Terms
Environmental Exposure
Forced Expiratory Volume
Lung / physiopathology*
Lung Diseases / physiopathology*
Middle Aged
Occupational Diseases / physiopathology*
Sulfur Dioxide*
Vital Capacity
Reg. No./Substance:
7446-09-5/Sulfur Dioxide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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